26 - Wilms Tumor Vs Neuroblastoma

The above video is a case of Wilm's Tumor on CT scan of abdomen :

The Wilms Tumor is differentiated from NB based on the following findings :

1)NB usually crosses midline, Wilm’s usually does not.

2)Calcification common in NB (90%), rare in Wilm’s  (10 – 15%).

3)Vessel encasement common in NB, displacement common in Wilm’s.

4)Wilms tumor is intrarenal whereas NB is extrarenal.

5)Retroperitoneal lymphadenopathy or contiguous extension of the primary tumor in the retroperitoneal space occurres frequently in neuroblastoma, and is seldom seen in Wilms tumor.

6)Distortion of the renal calyces is very specific for Wilms tumor; hydronephrosis can occcur in both.

7)NB younger age group (less than 2 years of age), Wilm’s slightly older age group : peak 3 – 4 years of age.

8)NB poorly marginated, Wilm’s = Well circumscribed.